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Article

Conversion of protein farnesyltransferase to a geranylgeranyltransferase.

Biochemistry - 15 Aug 2006

Terry Kimberly L, Casey Patrick J, Beese Lorena S

Abstract excerpt

Posttranslational modifications are essential for the proper function of a number of proteins in the cell. One such modification, the covalent attachment of a single isoprenoid lipid (prenylation), is carried out by the CaaX prenyltransferases, protein farnesyltransferase (FTase) and protein geranylgeranyltransferase type-I (GGTase-I). Substrate proteins of these two enzymes are involved in a variety of cellular...

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Identifiers

PMID: 16893176
DOI: 10.1021/bi060295e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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