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Article

Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito.

Nature - 19 Mar 1998

Billker O, Lindo V, Panico M, Etienne A E, Paxton T, Dell A, Rogers M, Sinden R E, Morris H R

Abstract excerpt

Malaria is transmitted from vertebrate host to mosquito vector by mature sexual blood-living stages called gametocytes. Within seconds of ingestion into the mosquito bloodmeal, gametocytes undergo gametogenesis. Induction requires the simultaneous exposure to at least two stimuli in vitro: a drop in bloodmeal temperature to 5 degrees C below that of the vertebrate host, and a rise in pH from 7.4 to 8.0-8.2. In...

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PMID: 9521324
DOI: 10.1038/32667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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