Article
Host 5-HT affects <i>Plasmodium</i> transmission in mosquitoes via modulating mosquito mitochondrial homeostasis
2024-02-21
Abstract excerpt
<h4>SUMMARY</h4> Malaria parasites hijack the metabolism of their mammalian host during the blood-stage cycle. Anopheles mosquitoes depend on mammalian blood to survive and to transmit malaria parasites. However, it remains understudied whether changes in host metabolism affect parasite transmission in mosquitoes. In this study, we discovered that Plasmodium infection significantly decreased the levels of the t...
Topics
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- Heme Oxygenase-1 and Carbon Monoxide
- Insect symbiosis and bacterial influences
- Invertebrate Immune Response Mechanisms
- Malaria Research and Control
- Mosquito-borne diseases and control
- Neurobiology and Insect Physiology Research
- Toxoplasma gondii Research Studies
- Trypanosoma species research and implications
Identifiers and source
- Literature Corpus work
- afdd4be5-1881-5d0f-9065-8ad91174958a
- DOI
- 10.1101/2024.02.19.580972
