Article
Phenotypic convergence and divergence of surface immunoglobulin and CD40 signals.
Scandinavian journal of immunology - 1 Mar 1998
Axcrona K, Akerblad P, Leanderson T
Abstract excerpt
Both anti-CD40 antibodies and anti-immunoglobulin (Ig) coupled to Sepharose induced proliferation of resting B cells and suppressed lipopolysaccharide (LPS)-induced B-cell differentiation to immunoglobulin secretion at comparable levels determined with the plaque-forming assay and Ig RNA steady s...
Topics
- Animals
- Antibodies
- B-Lymphocytes
- CD40 Antigens
- Cell Cycle
- Down-Regulation
- Female
- Immunoconjugates
- Lipopolysaccharides
- Lymphocyte Activation
- Male
- Mice
- Mice, Inbred BALB C
- Phenotype
- Receptors, Antigen, B-Cell
- Sepharose
- Signal Transduction
- T-Lymphocytes