Article
The Byr2 kinase translocates to the plasma membrane in a Ras1-dependent manner.
Biochemical and biophysical research communications - 17 Mar 1998
Bauman P, Cheng Q C, Albright C F
Abstract excerpt
The activation of mitogen-activated protein kinase cascades by the Ras GTPase is an evolutionarily conserved signal transduction mechanism. To better understand the interaction between Ras and its target kinase, we study the yeast Schizosaccharomyces pombe where the Ras1 GTPase activates the Byr2 kinase. Cell fractionation and immunofluorescence showed that Ras1 was localized to the plasma membrane and that Byr2...
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