Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Sept 2003

Dong Xiangwen, Mitchell David A, Lobo Sandra, Zhao Lihong, Bartels Douglas J, Deschenes Robert J

Abstract excerpt

Subcellular localization of Ras proteins to the plasma membrane is accomplished in part by covalent attachment of a farnesyl moiety to the conserved CaaX box cysteine. Farnesylation targets Ras to the endoplasmic reticulum (ER), where additional processing steps occur, resulting in translocation of Ras to the plasma membrane. The mechanism(s) by which this occurs is not well understood. In this report, we show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyltransferases
Share to Adenosine Triphosphatases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Membrane

Share to Palmitic Acids

Share to Protein Processing, Post-Translational

Share to Protein Transport

Share to ras Proteins

Share to Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 12944483
DOI: 10.1128/MCB.23.18.6574-6584.2003
PMCID: PMC193718

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae.PMID 12944483Read ↗

Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins.Semantic proximity Read ↗

Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases.Semantic proximity Read ↗

Plasma membrane localization of Ras requires class C Vps proteins and functional mitochondria in Saccharomyces cerevisiae.Semantic proximity Read ↗

Ras membrane targeting is essential for glucose signaling but not for viability in yeast.Semantic proximity Read ↗

Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway.Semantic proximity Read ↗

Global analysis of protein palmitoylation in yeast.Semantic proximity Read ↗

Rap2 function requires palmitoylation and recycling endosome localization.Semantic proximity Read ↗

Plasma membrane localization is required for RasA-mediated polarized morphogenesis and virulence of Aspergillus fumigatus.Semantic proximity Read ↗

Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway.Semantic proximity Read ↗

The Activation of ARF1 Is Dynamically Regulated by its Palmitoylation.Semantic proximity Read ↗

Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.