Article
Role for PKC alpha and PKC epsilon in down-regulation of CFTR mRNA in a human epithelial liver cell line.
Journal of hepatology - 1 Feb 1998
Kang-Park S, Dray-Charier N, Munier A, Brahimi-Horn C, Veissiere D, Picard J, Capeau J, Cherqui G, Lascols O
Abstract excerpt
BACKGROUND/AIMS: In the liver, intrahepatic biliary cells are the sole site of expression of the cystic fibrosis transmembrane conductance regulator, the product of the cystic fibrosis gene. We examined the regulation of cystic fibrosis transmembrane conductance regulator gene expression by protein kinase C in the recently characterized human liver epithelial BC1 cell line which expresses, at early confluence,...
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