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Article

Effect of phorbol ester and platelet-derived growth factor on protein kinase C in rat hepatic stellate cells.

Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2007

Kobayashi Yoshimasa, Bridle Kim R, Ramm Grant A, O'neill Rosemary, Britton Robert S, Bacon Bruce R

Abstract excerpt

BACKGROUND/AIMS: Hepatic stellate cells (HSC) play a key role in hepatic fibrogenesis and thus, it is important to understand the intracellular signalling pathways that influence their behaviour. This study investigated the expression and regulation of protein kinase C (PKC) in HSC. RESULTS: Western blot analysis indicates that rat HSC express at least four PKC isoforms, PKC-alpha, PKC-delta, PKC-epsilon and...

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PMID: 17845534
DOI: 10.1111/j.1478-3231.2007.01573.x

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MARCKS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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