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Article

Bisphenol A inhibits Cl(-) secretion by inhibition of basolateral K+ conductance in human airway epithelial cells.

The Journal of pharmacology and experimental therapeutics - 1 Jul 2002

Ito Yasushi, Sato Shinji, Son Masami, Kondo Masashi, Kume Hiroaki, Takagi Kenzo, Yamaki Kenichi

Abstract excerpt

There has been growing concern about the potential threat of hormone-disrupting chemicals like bisphenol A to various aspects of animal and human health. We studied the effects of bisphenol A on the Cl(-) secretion in human airway epithelial Calu-3 cells. Pretreatment with bisphenol A (IC(50) = 60 microM, for 30 min) prevented isoproterenol (10 nM)-generated short-circuit current (I(sc)) more potently than...

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Identifiers

PMID: 12065703
DOI: 10.1124/jpet.302.1.80

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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