Article
Contribution of selective HLA-DRB1/DQB1 alleles and haplotypes to the genetic susceptibility of type 1 diabetes among Lebanese and Bahraini Arabs.
The Journal of clinical endocrinology and metabolism - 1 Sept 2005
Al-Jenaidi Fayza A, Wakim-Ghorayeb Saria F, Al-Abbasi Abduljabbar, Arekat Mona R, Irani-Hakime Noha, Najm Pierre, Al-Ola Khadija, Motala Ayesha A, Almawi Wassim Y
Abstract excerpt
CONTEXT: Human leukocyte antigen (HLA) class II genes contribute to the genetic susceptibility of type 1 diabetes (T1D), and both susceptible and protective alleles were implicated with its pathogenesis, which varies among various ethnic/racial groups. OBJECTIVE: This study investigated the heterogeneity in HLA class II haplotypes distribution among Bahraini and Lebanese T1D patients. DESIGN: This was a...
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