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Article

Experimental Autoimmune Encephalomyelitis Is Exacerbated in Mice Lacking the <i>NOS2</i> Gene

1 Mar 1998

Abstract excerpt

Nitric oxide is believed to be a prominent mediator of inflammation based in part on the correlative expression of the inducible nitric oxide synthase (iNOS) gene in various pathologies. The resulting high output of the highly reactive molecule nitric oxide is then believed to play an important role in the evolving inflammatory response. Studies have shown that iNOS and nitric oxide are present in the tissues of...

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PMID: 9510198
DOI: 10.4049/jimmunol.160.6.2940

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