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Article

The extracellular calcium-sensing receptor: its role in health and disease.

Annual review of medicine - 1 Jan 1998

Brown E M, Pollak M, Hebert S C

Abstract excerpt

The recent cloning of an extracellular calcium (Ca2+o)-sensing receptor (CaR) from parathyroid, kidney and other cell types has clarified the mechanisms through which Ca2+o exerts its direct actions on various cells and tissues. In the parathyroid, the CaR mediates the inhibitory effects of Ca2+o...

Topics

Absorption
Calcium
Cations, Divalent
Cell Division
Cloning, Molecular
Disease
Gene Expression Regulation
Genetic Diseases, Inborn
Health
Homeostasis
Humans
Hypercalcemia
Hyperparathyroidism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kidney

Kidney Concentrating Ability

Kidney Cortex

Kidney Medulla

Kidney Tubules, Collecting

Source

Identifiers

PMID: 9509247
DOI: 10.1146/annurev.med.49.1.15

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9509247-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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