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Article

The extracellular calcium-sensing receptor: its role in health and disease.

Annual review of medicine - 1 Jan 1998

Brown E M, Pollak M, Hebert S C

Abstract excerpt

The recent cloning of an extracellular calcium (Ca2+o)-sensing receptor (CaR) from parathyroid, kidney and other cell types has clarified the mechanisms through which Ca2+o exerts its direct actions on various cells and tissues. In the parathyroid, the CaR mediates the inhibitory effects of Ca2+o on parathyroid hormone (PTH) secretion and likely on expression of the PTH gene and parathyroid cellular...

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Source

Identifiers

PMID: 9509247
DOI: 10.1146/annurev.med.49.1.15

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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