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Article

Mutations in the calcium-sensing receptor and their clinical implications.

Hormone research - 1 Jan 1997

Brown E M

Abstract excerpt

Specialized cells (i.e., parathyroid chief cells) that sense changes in the extracellular calcium concentration are a key element in mineral ion homeostasis. The Ca2+o-sensing receptor (CaR) originally cloned from bovine parathyroid is also present in multiple nephron segments involved in Ca2+o h...

Topics

Calcium
Calcium Metabolism Disorders
Calcium-Binding Proteins
GTP-Binding Proteins
Homeostasis
Humans
Hyperparathyroidism
Magnesium
Mutation
Receptors, Calcium-Sensing
Receptors, Cell Surface
Signal Transduction

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Identifiers

PMID: 9362389
DOI: 10.1159/000185516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9362389-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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