Article
Mutations in the calcium-sensing receptor and their clinical implications.
Hormone research - 1 Jan 1997
Brown E M
Abstract excerpt
Specialized cells (i.e., parathyroid chief cells) that sense changes in the extracellular calcium concentration are a key element in mineral ion homeostasis. The Ca2+o-sensing receptor (CaR) originally cloned from bovine parathyroid is also present in multiple nephron segments involved in Ca2+o homeostasis as well as in other sites that are not, such as brain, lung, large and small intestine. The physiological...
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