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Article

The calcium-sensing receptor in normal physiology and pathophysiology: a review.

Critical reviews in clinical laboratory sciences - 1 Jan 2005

Tfelt-Hansen Jacob, Brown Edward M

Abstract excerpt

The discovery of a G protein-coupled, calcium-sensing receptor (CaR) a decade ago and of diseases caused by CaR mutations provided unquestionable evidence of the CaR's critical role in the maintenance of systemic calcium homeostasis. On the cell membrane of the chief cells of the parathyroid glands, the CaR "senses" the extracellular calcium concentration and, subsequently, alters the release of parathyroid...

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Identifiers

PMID: 15697170
DOI: 10.1080/10408360590886606

Genes

PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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