Sensing of extracellular Ca2+ by parathyroid and kidney cells: cloning and characterization of an extracellular Ca(2+)-sensing receptor.

doi:10.1016/0272-6386(95)90118-3

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Article

Sensing of extracellular Ca2+ by parathyroid and kidney cells: cloning and characterization of an extracellular Ca(2+)-sensing receptor.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Mar 1995

Brown E M, Pollak M, Hebert S C

Abstract excerpt

The ability of the parathyroid cell to sense minute fluctuations in the extracellular ionized calcium concentration (Ca2+ o) is essential for maintaining mineral ion homeostasis. However, the mechanism(s) through which the parathyroid cell and other cells recognize and respond to changes in Ca2+...

Topics

Animals
Calcium
Cloning, Molecular
Humans
Hypercalcemia
Hyperparathyroidism
Infant, Newborn
Kidney
Mutation
Parathyroid Glands
Receptors, Calcium-Sensing
Receptors, Cell Surface

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Identifiers

PMID: 7872334
DOI: 10.1016/0272-6386(95)90118-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7872334-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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