The cloning of extracellular Ca(2+)-sensing receptors from parathyroid and kidney: molecular mechanisms of extracellular Ca(2+)-sensing.

doi:10.1093/jn/125.suppl_7.1965S

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Article

The cloning of extracellular Ca(2+)-sensing receptors from parathyroid and kidney: molecular mechanisms of extracellular Ca(2+)-sensing.

The Journal of nutrition - 1 Jul 1995

Brown E M, Pollak M, Chou Y H, Seidman C E, Seidman J G, Hebert S C

Abstract excerpt

The parathyroid cell detects changes in the extracellular ionized calcium concentration (Ca2 + o) with exquisite sensitivity, but the mechanisms through which it senses Ca2 + o have remained obscure. Recently, we isolated a cDNA encoding a Ca2 + o-sensing receptor from bovine parathyroid using ex...

Topics

Animals
Calcium
Cloning, Molecular
Homeostasis
Kidney
Metabolism, Inborn Errors
Mutation
Oocytes
Parathyroid Glands
Receptors, Cell Surface
Signal Transduction

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