Article
Structure and function of the extracellular calcium-sensing receptor (Review).
International journal of molecular medicine - 1 Aug 1999
Bai M
Abstract excerpt
The extracellular calcium-sensing receptor (CaR) originally cloned from bovine parathyroid gland is a G protein-coupled receptor. The physiological relevance of the cloned CaR for sensing and regulating the extracellular calcium concentration has been established by identifying hyper- and hypocalcemic disorders resulting from inactivating and activating mutations, respectively, in the CaR. The cloned CaR has been...
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