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Article

Comparison of the gating behaviour of human and murine cystic fibrosis transmembrane conductance regulator Cl<sup>−</sup> channels expressed in mammalian cells

1 Apr 1998

Abstract excerpt

1. To investigate the function of the murine cystic fibrosis transmembrane conductance regulator (CFTR), a full-length cDNA encoding wild-type murine CFTR was assembled and stably expressed in Chinese hamster ovary (CHO) cells. 2. Like human CFTR, murine CFTR formed Cl- channels that were regulated by cAMP-dependent phosphorylation and intracellular ATP. However, murine CFTR Cl- channels had a reduced...

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Identifiers

PMID: 9508803
DOI: 10.1111/j.1469-7793.1998.379bq.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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