Article
CFTR regulation of epithelial sodium channel.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Qadri Yawar J, Cormet-Boyaka Estelle, Benos Dale J, Berdiev Bakhrom K
Abstract excerpt
Cystic fibrosis (CF) is a lethal genetic disorder, characterized by both clinical and genetic complexities, and arises as a result of mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The gene encodes a Cl(-) channel belonging to the ABC (ATP Binding Cassette) superfamily of transporters. The members of this superfamily use ATP hydrolysis to fulfill their function as active...
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