Article
In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy.
The Journal of cell biology - 23 Mar 1998
Masson R, Lefebvre O, Noël A, Fahime M E, Chenard M P, Wendling C, Kebers F, LeMeur M, Dierich A, Foidart J M, Basset P, Rio M C
Abstract excerpt
Stromelysin-3 (ST3; Basset, P., J.P. Bellocq, C. Wolf, I. Stoll, P. Hutin, J.M. Limacher, O.L. Podhajcer, M.P. Chenard, M.C. Rio, P. Chambon. 1990. Nature. 348:699-704) is a matrix metalloproteinase (MMP) expressed in mesenchymal cells located close to epithelial cells, during physiological and pathological tissue remodeling processes. In human carcinomas, high ST3 levels are associated with a poor clinical...
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