Article
A causative role of stromelysin-3 in extracellular matrix remodeling and epithelial apoptosis during intestinal metamorphosis in Xenopus laevis.
The Journal of biological chemistry - 29 Jul 2005
Fu Liezhen, Ishizuya-Oka Atsuko, Buchholz Daniel R, Amano Tosikazu, Matsuda Hiroki, Shi Yun-Bo
Abstract excerpt
The matrix metalloproteinases are a family of proteases capable of degrading various components of the extracellular matrix. Expression studies have implicated the involvement of the matrix metalloproteinase stromelysin-3 (ST3) in tissue remodeling and pathogenesis. However, the in vivo role of ST3 has been difficult to study because of a lack of good animal models. Here we used intestinal remodeling during...
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