Article
A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 1996
Anand-Apte B, Bao L, Smith R, Iwata K, Olsen B R, Zetter B, Apte S S
Abstract excerpt
The family of tissue inhibitors of metalloproteinases (TIMPs) presently numbers four distinct gene products that are specific inhibitors of the matrix metalloproteinases (MMPs). The local balance between MMPs and TIMPs is believed to play a major role in extracellular matrix (ECM) remodeling duri...
Topics
- Animals
- Blindness
- Breast Neoplasms
- Extracellular Matrix
- Humans
- Melanoma
- Mutation
- Neoplasms
- Proteins
- Tissue Inhibitor of Metalloproteinase-3
- Transfection
- Tumor Cells, Cultured