Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coexpression of stromelysin-3 and insulin-like growth factor II in tumors of ectodermal, mesodermal, and endodermal origin: indicator of a fetal cell phenotype.

The Journal of clinical endocrinology and metabolism - 1 Jun 1997

Singer C F, Rasmussen A, Lippman M E, Cullen K J

Abstract excerpt

Stromelysin-3 (ST-3) is thought to play an important role in invasion and tumor progression. We have analyzed ST-3 expression in fibroblasts with defined topographical relations to breast cancers. We demonstrate that these fibroblasts exhibit the same distinctive pattern of messenger ribonucleic acid (mRNA) expression that we have previously shown for insulin-like growth factor II (IGF-II). Tumor-derived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Colonic Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblasts

Share to Immunohistochemistry

Share to Phenotype

Share to RNA, Messenger

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 9177406
DOI: 10.1210/jcem.82.6.4023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coexpression of stromelysin-3 and insulin-like growth factor II in tumors of ectodermal, mesodermal, and endodermal origin: indicator of a fetal cell phenotype.PMID 9177406Read ↗

In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy.Semantic proximity Read ↗

Stromelysin-3 suppresses tumor cell apoptosis in a murine model.Semantic proximity Read ↗

Elevated stromelysin-1 and reduced collagenase-IV expression in invasive rat embryo fibroblasts expressing E1A deletion mutants + T24-H-ras.Semantic proximity Read ↗

Insulin‐like growth factor binding protein 3 as an anticancer molecule in Ewing's sarcomaSemantic proximity Read ↗

Roles of IGFBP-3 in cell migration and growth in an endophytic tongue squamous cell carcinoma cell lineSemantic proximity Read ↗

Active stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinase.Semantic proximity Read ↗

Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion.Semantic proximity Read ↗

IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms.Semantic proximity Read ↗

A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth.Semantic proximity Read ↗

Mutational analysis of the cleavage of the cancer-associated laminin receptor by stromelysin-3 reveals the contribution of flanking sequences to site recognition and cleavage efficiency.Semantic proximity Read ↗

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.Semantic proximity Read ↗

The Int-2/Fgf-3 oncogene product is secreted and associates with extracellular matrix: implications for cell transformation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.