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Article

Matrix metalloproteinase 11 (MMP‐11; stromelysin‐3) and synthetic inhibitors

18 May 2006

Abstract excerpt

Matrix metalloproteinase (MMP)-11, or Stromelysin 3, is a particular member of MMP family, a group of zinc-dependent endopeptidases involved in matrix degradation and tissue remodeling. Despite intense efforts since its first characterization 15 years ago, its role and target substrates in different diseases remain largely unknown. While mice with MMP-11 deficiency display no particular phenotype, analysis of...

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PMID: 16710861
DOI: 10.1002/med.20066

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