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Article

Dickkopf-3 in Human Malignant Tumours: A Clinical Viewpoint.

Anticancer research - 1 Nov 2020

Lee Eun-Ju, Nguyen Que Thanh Thanh, Lee Mooyul

Abstract excerpt

Dickkopf-3 (DKK3), also known as REIC, is a secreted glycoprotein. DKK3 is aberrantly expressed in various types of human malignant tumours. Promoter methylation status, intracellular protein expression, and protein expression in tumour vessels are significantly correlated with clinical prognostic factors, including survival. In malignant cells, DKK3 is involved in the induction of apoptosis, inhibition of...

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Identifiers

PMID: 33109534
DOI: 10.21873/anticanres.14617

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