Article
Genetic predictors of common disease: apolipoprotein E genotype as a paradigm.
Annals of epidemiology - 1 Jul 1997
Jarvik G P
Abstract excerpt
PURPOSE: Genetic variation of a common genetic polymorphism at the structural locus for apolipoprotein E (apoE) has been associated with risk of elevated serum lipids, coronary artery disease, and Alzheimer disease, all of which are multifactoral disorders and are inherited in a complex fashion. Although the apoE polymorphism is only one risk factor in a complex pattern of inheritance, it gives us a foothold into...
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