Article
Associations between apolipoprotein E genotype and circulating F2-isoprostane levels in humans.
Lipids - 1 Apr 2005
Dietrich Marion, Hu Youqing, Block Gladys, Olano Estibaliz, Packer Lester, Morrow Jason D, Hudes Mark, Abdukeyum Gulbahar, Rimbach Gerald, Minihane Anne M
Abstract excerpt
Apolipoprotein E (apoE), an important determinant of plasma lipoprotein metabolism, has three common alleles (epsilon2, epsilon3, and epsilon4). Population studies have shown that the risk of diseases characterized by oxidative damage, such as coronary heart disease and Alzheimer's disease, is significantly higher in epsilon4 carriers. We evaluated the association between apoE genotypes and plasma F2-isoprostane...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
