Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice.

Circulation - 3 Mar 1998

Shah P K, Nilsson J, Kaul S, Fishbein M C, Ageland H, Hamsten A, Johansson J, Karpe F, Cercek B

Abstract excerpt

BACKGROUND: We previously reported marked inhibitory effects of recombinant apolipoprotein (apo) A-I(Milano)/phospholipid complex (A-I[Milano]/PC) on neointimal lesions in balloon-injured iliofemoral arteries of hypercholesterolemic rabbits. In this study, we tested the hypothesis that apo A-I(Milano)/PC would inhibit aortic atherosclerosis in apo E-deficient mice. METHODS AND RESULTS: Thirty-five apo E-deficient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Cholesterol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

Share to Macrophages

Share to Mice, Inbred C57BL

Share to Mutation

Share to Recombinant Proteins

Source

Identifiers

PMID: 9498542
DOI: 10.1161/01.cir.97.8.780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice.PMID 9498542Read ↗

Comparative Effects of Diet-Induced Lipid Lowering Versus Lipid Lowering Along With Apo A-I Milano Gene Therapy on Regression of Atherosclerosis.Semantic proximity Read ↗

Apolipoprotein A-I(Milano): current perspectives.Semantic proximity Read ↗

The Role of An Experimental Model of Atherosclerosis: apoE-knockout Mice in Developing New Drugs against AtherogenesisSemantic proximity Read ↗

Lipoprotein (a) is an Upstream Mediator of Aortic StenosisSemantic proximity Read ↗

Apolipoprotein A-I and the molecular variant apoA-I(Milano): evaluation of the antiatherogenic effects in knock-in mouse model.Semantic proximity Read ↗

Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent.Semantic proximity Read ↗

Cardiac and vascular phenotypes in the apolipoprotein E-deficient mouseSemantic proximity Read ↗

A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice.Semantic proximity Read ↗

Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse.Semantic proximity Read ↗

Atherosclerosis and the protective role played by different proteins in apolipoprotein E-deficient mice.Semantic proximity Read ↗

Apolipoprotein A-I protection against atherosclerosis is dependent on genetic background.Semantic proximity Read ↗

Apolipoprotein A-I Mimetic Peptides: Discordance Between In Vitro and In Vivo Properties-Brief Report.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.