Article
Apolipoprotein A-I Mimetic Peptides: Discordance Between In Vitro and In Vivo Properties-Brief Report.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2017
Ditiatkovski Michael, Palsson Jonatan, Chin-Dusting Jaye, Remaley Alan T, Sviridov Dmitri
Abstract excerpt
OBJECTIVE: Apolipoprotein A-I (apoA-I) mimetic peptides have antiatherogenic properties of high-density lipoprotein in vitro and have been shown to inhibit atherosclerosis in vivo. It is unclear, however, if each in vitro antiatherogenic property of these peptides translates to a corresponding activity in vivo, and if so, which of these contributes most to reduce atherosclerosis. APPROACH AND RESULTS: The effect...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
