Article
Human leukocyte antigen (HLA)-C and its association with HIV-1 transmission in discordant couple and mother-to-child cohorts.
Immunogenetics - 1 Nov 2018
Bardeskar N S, Chavan V, Ahir-Bist S, Nanavati R, Samant-Mavani P, Mehta P, Mania-Pramanik Jayanti
Abstract excerpt
Human leukocyte antigen (HLA) molecules play a key role in regulating the immune response towards infectious agents like human immunodeficiency virus type-1 (HIV-1). They have been shown to influence transmission as well as the progression of HIV-1 towards acquired immune deficiency syndrome (AIDS). Roles of HLA-A and HLA-B have been documented extensively; however, HLA-C has been poorly studied. In the present...
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