Article
Functional characterization and evolutionary history of two aryl hydrocarbon receptor isoforms (AhR1 and AhR2) from avian species.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Sept 2007
Yasui Tomoko, Kim Eun-Young, Iwata Hisato, Franks Diana G, Karchner Sibel I, Hahn Mark E, Tanabe Shinsuke
Abstract excerpt
Dioxins including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induce various toxic effects through the aryl hydrocarbon receptor (AhR) signaling pathway. Here, we investigated the structural and functional characteristics and molecular evolution of multiple AhRs in black-footed albatross (Phoebastria nigripes) and common cormorant (Phalacrocorax carbo). We report the complementary DNA sequences of two distinct...
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