Article
Mutation analysis of ras gene in the liver of European eel (Anguilla anguilla L.) exposed to benzo[a]pyrene.
Marine pollution bulletin - 1 Dec 2006
Nogueira Patrícia R, Lourenço Joana, Mendo Sónia, Rotchell Jeanette M
Abstract excerpt
Ras is regarded as one of the most important genes involved in carcinogenesis. Such genes have been characterised in several fish species and the presence of ras mutations have already been described in fish populations from hydrocarbon contaminated areas and following experimental exposure to specific contaminants. The aims of this study were to evaluate the DNA integrity by comet assay, to isolate the normal...
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