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Article

Use of a two-color genetic screen to identify a domain of the global regulator Lrp that is specifically required for pap phase variation.

Journal of bacteriology - 1 Mar 1998

Kaltenbach L, Braaten B, Tucker J, Krabbe M, Low D

Abstract excerpt

The global regulator Lrp plays a central role as both a repressor and an activator in Pap phase variation. Unlike most other members of the Lrp regulon such as ilvIH, activation of papBA transcription requires the coregulator PapI and is methylation dependent. We developed a two-color genetic screen to identify Lrp mutations that inhibit Pap phase variation but still activate ilvIH transcription, reasoning that...

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Identifiers

PMID: 9495762
DOI: 10.1128/JB.180.5.1224-1231.1998
PMCID: PMC107011

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Use of a two-color genetic screen to identify a domain of the global regulator Lrp that is specifically required for pap phase variation.PMID 9495762Read ↗

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