Article
Use of a two-color genetic screen to identify a domain of the global regulator Lrp that is specifically required for pap phase variation.
Journal of bacteriology - 1 Mar 1998
Kaltenbach L, Braaten B, Tucker J, Krabbe M, Low D
Abstract excerpt
The global regulator Lrp plays a central role as both a repressor and an activator in Pap phase variation. Unlike most other members of the Lrp regulon such as ilvIH, activation of papBA transcription requires the coregulator PapI and is methylation dependent. We developed a two-color genetic scr...
Topics
- Amino Acid Sequence
- Amino Acid Substitution
- Bacterial Proteins
- Binding Sites
- DNA Methylation
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Fimbriae, Bacterial
- Genetic Techniques
- Leucine
- Leucine-Responsive Regulatory Protein
- Molecular Sequence Data