Article
The essential role of the promoter-proximal subunit of CAP in pap phase variation: Lrp- and helical phase-dependent activation of papBA transcription by CAP from -215.
Molecular microbiology - 1 Mar 2001
Weyand N J, Braaten B A, van der Woude M, Tucker J, Low D A
Abstract excerpt
Catabolite gene activator protein (CAP) is essential for the expression of Pap pili by uropathogenic Escherichia coli. Both in vitro and in vivo analyses indicate that binding of cAMP-CAP centred at 215.5 bp upstream of the papBA promoter is essential for activation of transcription. CAP-dependent activation of papBA requires binding of the leucine-responsive regulatory protein (Lrp) at binding sites that extend...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Cyclic AMP Receptor Protein
- DNA, Bacterial
- DNA-Binding Proteins
- DNA-Directed RNA Polymerases
- Escherichia coli
- Escherichia coli Proteins
- Fimbriae Proteins