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Article

Regulatory elements required for human angiotensinogen expression in HepG2 cells are dispensable in transgenic mice.

Hypertension (Dallas, Tex. : 1979) - 1 Mar 1998

Yang G, Sigmund C D

Abstract excerpt

Previous researchers have identified two sequences present upstream (angiotensinogen gene-activating element [AGE2]) and downstream (d61-2) of the human angiotensinogen gene that act as cell-specific enhancers of transcription in transiently transfected HepG2 cells. To examine the importance of these two sequences in regulating tissue- and cell-specific expression of the gene in vivo, we generated transgenic mice...

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Identifiers

PMID: 9495255
DOI: 10.1161/01.hyp.31.3.734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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