Article
Proximal and core DNA elements are required for efficient angiotensinogen promoter activation during adipogenic differentiation.
The Journal of biological chemistry - 15 Jul 1993
Tamura K, Tanimoto K, Ishii M, Murakami K, Fukamizu A
Abstract excerpt
Angiotensinogen is abundantly expressed in adipose tissue as well as in liver where it is mainly produced. To address the mechanism of this adipogenic expression, promoter regions of the mouse angiotensinogen gene are fused to the chloramphenicol acetyltransferase reporter gene and stably transfected into 3T3-L1 preadipocytes. Promoter activity correlates well with an increase of mRNA levels during adipogenic...
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