Article
Oncogenes and epithelial cell transformation.
Seminars in cancer biology - 1 Apr 1994
Reichmann E
Abstract excerpt
More than 80% of the tumors occurring in man are carcinomas. Despite the prevalence of these epithelial tumors most in vitro studies of oncogenesis have employed mesenchymal rather than epithelial cells. As a result, a detailed understanding of the molecular mechanisms of carcinoma formation and an exact definition of the malignant transformed epithelial phenotype are lacking. Taking into account that the genesis...
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