Formation of large nucleoprotein complexes upon binding of the high-mobility-group (HMG) box B-domain of HMG1 protein to supercoiled DNA.

doi:10.1046/j.1432-1327.1998.2510427.x

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Article

Formation of large nucleoprotein complexes upon binding of the high-mobility-group (HMG) box B-domain of HMG1 protein to supercoiled DNA.

European journal of biochemistry - 15 Jan 1998

Stros M, Reich J

Abstract excerpt

High-mobility group (HMG) 1 is a relatively highly abundant chromosomal protein with structural- rather than sequence-specific preference for binding to DNA. HMG1 has two highly related, folded domains A and B (HMG boxes), attached by a short basic region to an acidic C-terminal domain. We have s...

Topics

Amino Acid Sequence
Binding Sites
DNA
Electrophoresis
High Mobility Group Proteins
Microscopy, Electron
Models, Molecular
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Nucleoproteins
Protein Conformation

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