Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histone H1 Differentially Inhibits DNA Bending by Reduced and Oxidized HMGB1 Protein.

PloS one - 1 Jan 2015

Štros Michal, Polanská Eva, Kučírek Martin, Pospíšilová Šárka

Abstract excerpt

HMGB1 protein and linker histone H1 have overlapping binding sites in the nucleosome. HMGB1 has been implicated in many DNA-dependent processes in chromatin involving binding of specific proteins, including transcription factors, to DNA sites pre-bent by HMGB1. HMGB1 can also act as an extracellular signaling molecule by promoting inflammation, tumor growth a metastasis. Many of the intra- and extracellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cysteine
Share to DNA, Superhelical
Share to Histones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HMGB1 Protein

Share to Models, Molecular

Share to Nucleosomes

Share to Oxidation-Reduction

Source

Open in PubMed Open full text

Identifiers

PMID: 26406975
DOI: 10.1371/journal.pone.0138774
PMCID: PMC4583294

Genes

HMGB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histone H1 Differentially Inhibits DNA Bending by Reduced and Oxidized HMGB1 Protein.PMID 26406975Read ↗

HMGB1: The jack‐of‐all‐trades protein is a master DNA repair mechanicSemantic proximity Read ↗

HMGB1-mediated DNA bending: Distinct roles in increasing p53 binding to DNA and the transactivation of p53-responsive gene promoters.Semantic proximity Read ↗

Multiple functions of HMGB1 in cancerSemantic proximity Read ↗

High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic StrategiesSemantic proximity Read ↗

Role of HMGB1 and its associated signaling pathways in human malignanciesSemantic proximity Read ↗

Emerging roles for HMGB1 protein in immunity, inflammation, and cancerSemantic proximity Read ↗

The dual role and therapeutic potential of high-mobility group box 1 in cancerSemantic proximity Read ↗

The DNA chaperone HMGB1 facilitates ACF/CHRAC-dependent nucleosome sliding.Semantic proximity Read ↗

The DNA architectural protein HMGB1 displays two distinct modes of action that promote enhanceosome assembly.Semantic proximity Read ↗

Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine functionSemantic proximity Read ↗

High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage.Semantic proximity Read ↗

High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignanciesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.