Article
The Mof2/Sui1 protein is a general monitor of translational accuracy.
Molecular and cellular biology - 1 Mar 1998
Cui Y, Dinman J D, Kinzy T G, Peltz S W
Abstract excerpt
Although it is essential for protein synthesis to be highly accurate, a number of cases of directed ribosomal frameshifting have been reported in RNA viruses, as well as in procaryotic and eucaryotic genes. Changes in the efficiency of ribosomal frameshifting can have major effects on the ability...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Codon
- Eukaryotic Initiation Factor-1
- Frameshift Mutation
- Fungal Proteins
- Genes, Fungal
- Humans
- Molecular Sequence Data
- Mutagenesis
- Paromomycin
- Peptide Chain Initiation, Translational
- Peptide Initiation Factors
- Polyribosomes
- Protein Biosynthesis
- Ribosomes
- Saccharomyces cerevisiae