Article
Translational maintenance of frame: mutants of Saccharomyces cerevisiae with altered -1 ribosomal frameshifting efficiencies.
Genetics - 1 Jan 1994
Dinman J D, Wickner R B
Abstract excerpt
A special site on the (+) strand of the L-A dsRNA virus induces about 2% of ribosomes translating the gag open reading frame to execute a -1 frameshift and thus produce the viral gag-pol fusion protein. Using constructs in which a -1 ribosomal frameshift at this site was necessary for expression...
Topics
- Base Sequence
- Escherichia coli
- Frameshift Mutation
- Genes, Fungal
- Genes, gag
- Genetic Complementation Test
- Genotype
- Meiosis
- Mutagenesis
- Open Reading Frames
- Phenotype
- Plasmids
- Protein Biosynthesis
- RNA Viruses
- RNA, Double-Stranded
- Ribosomes
- Saccharomyces cerevisiae
- beta-Galactosidase