Mof4-1 is an allele of the UPF1/IFS2 gene which affects both mRNA turnover and -1 ribosomal frameshifting efficiency.

Article

Mof4-1 is an allele of the UPF1/IFS2 gene which affects both mRNA turnover and -1 ribosomal frameshifting efficiency.

The EMBO journal - 15 Oct 1996

Cui Y, Dinman J D, Peltz S W

Abstract excerpt

The mof4-1 (maintenance of frame) allele in the yeast Saccharomyces cerevisiae was isolated as a chromosomal mutation that increased the efficiency of -1 ribosomal frameshifting at the L-A virus frameshift site and caused loss of M1, the satellite virus of L-A. Here, we demonstrate that strains h...

Topics

Alleles
Frameshifting, Ribosomal
Fungal Proteins
Genes, Reporter
Lac Operon
Mutagenesis
Paromomycin
RNA Helicases
RNA, Messenger
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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