Article
p53-Dependent Elevation of p21 Waf1 Expression by UV Light Is Mediated through mRNA Stabilization and Involves a Vanadate-Sensitive Regulatory System
1 Mar 1998
Abstract excerpt
Exposure of mammalian cells to adverse stimuli triggers the expression of numerous stress response genes, many of which are presumed to enhance cell survival. In this study, we examined the mechanisms contributing to the induction of p21Waf1 by stress and its influence on the survival of cells subjected to short-wavelength UVC irradiation. UVC was found to elevate p21Waf1 mRNA expression in mouse embryonal...
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