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Article

Legionella pneumophila catalase-peroxidases are required for proper trafficking and growth in primary macrophages.

Infection and immunity - 1 Aug 2003

Bandyopadhyay Purnima, Byrne Brenda, Chan Yolande, Swanson Michele S, Steinman Howard M

Abstract excerpt

Legionella pneumophila, a parasite of aquatic amoebae and pathogen of pulmonary macrophages, replicates intracellularly, utilizing a type IV secretion system to subvert the trafficking of Legionella-containing phagosomes. Defense against host-derived reactive oxygen species has been proposed as critical for intracellular replication. Virulence traits of null mutants in katA and katB, encoding the two Legionella...

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Identifiers

PMID: 12874332
DOI: 10.1128/IAI.71.8.4526-4535.2003
PMCID: PMC166045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Legionella pneumophila catalase-peroxidases are required for proper trafficking and growth in primary macrophages.PMID 12874332Read ↗

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