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Article

Regulation of periodontal ligament cell functions by interleukin-1beta.

Infection and immunity - 1 Mar 1998

Agarwal S, Chandra C S, Piesco N P, Langkamp H H, Bowen L, Baran C

Abstract excerpt

Periodontal ligament (PDL) cells maintain the attachment of the tooth to alveolar bone. These cells reside at a site in which they are challenged frequently by bacterial products and proinflammatory cytokines, such as interleukin-1beta (IL-1beta), during infections. In our initial studies we observed that IL-1beta down-regulates the osteoblast-like characteristics of PDL cells in vitro. Therefore, we examined the...

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Identifiers

PMID: 9488378
DOI: 10.1128/IAI.66.3.932-937.1998
PMCID: PMC107998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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