Article
LPS responsiveness in periodontal ligament cells is regulated by tumor necrosis factor-alpha.
Journal of dental research - 1 Nov 1995
Quintero J C, Piesco N P, Langkamp H H, Bowen L, Agarwal S
Abstract excerpt
Gingival fibroblasts function as accessory immune cells and are capable of synthesizing cytokines in response to lipopolysaccharides (LPS) from Gram-negative microbes. Recently, we have isolated, cloned, and characterized two cell lines which exhibit characteristics of periodontal ligament (PDL) cells. In this report, we demonstrate that PDL cells showing osteoblast-like phenotype are not LPS-responsive cells....
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