Article
LPS responsiveness in periodontal ligament cells is regulated by tumor necrosis factor-alpha.
Journal of dental research - 1 Nov 1995
Quintero J C, Piesco N P, Langkamp H H, Bowen L, Agarwal S
Abstract excerpt
Gingival fibroblasts function as accessory immune cells and are capable of synthesizing cytokines in response to lipopolysaccharides (LPS) from Gram-negative microbes. Recently, we have isolated, cloned, and characterized two cell lines which exhibit characteristics of periodontal ligament (PDL)...
Topics
- Alkaline Phosphatase
- Antigen-Presenting Cells
- Base Sequence
- Cell Line
- DNA Primers
- Fibroblasts
- Humans
- Interleukins
- Lipopolysaccharides
- Molecular Sequence Data
- Osteoblasts
- Osteocalcin
- Periodontal Ligament
- Phenotype
- RNA, Messenger
- Recombinant Proteins
- Time Factors
- Transforming Growth Factor beta