Effects of Activin A on the phenotypic properties of human periodontal ligament cells.

doi:10.1016/j.bone.2014.05.021

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

Effects of Activin A on the phenotypic properties of human periodontal ligament cells.

Bone - 1 Sept 2014

Sugii Hideki, Maeda Hidefumi, Tomokiyo Atsushi, Yamamoto Naohide, Wada Naohisa, Koori Katsuaki, Hasegawa Daigaku, Hamano Sayuri, Yuda Asuka, Monnouchi Satoshi, Akamine Akifumi

Abstract excerpt

Periodontal ligament (PDL) tissue plays an important role in tooth preservation by structurally maintaining the connection between the tooth root and the bone. The mechanisms involved in the healing and regeneration of damaged PDL tissue, caused by bacterial infection, caries and trauma, have been explored. Accumulating evidence suggests that Activin A, a member of the transforming growth factor-β (TGF-β)...

Topics

Activin Receptors
Activins
Animals
Cell Differentiation
Cell Proliferation
Chemotaxis
Female
Fibroblasts
Gene Expression Regulation
Humans
Interleukin-1beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Osteoblasts

Osteogenesis

Periodontal Ligament

Phenotype

Rats, Sprague-Dawley

Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 24928494
DOI: 10.1016/j.bone.2014.05.021

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of Activin A on the phenotypic properties of human periodontal ligament cells.PMID 24928494Read ↗

Rho plays a key role in TGF-β1-induced proliferation and cytoskeleton rearrangement of human periodontal ligament cells.Semantic proximity Read ↗

Phenotypic comparison of periodontal ligament cells in vivo and in vitro.Semantic proximity Read ↗

Regulation of gingival fibroblast phenotype by periodontal ligament cells in vitro.Semantic proximity Read ↗

Different Immunoregulation Roles of Activin A Compared With TGF-βSemantic proximity Read ↗

Tensile strength suppresses the osteogenesis of periodontal ligament cells in inflammatory microenvironments.Semantic proximity Read ↗

Autoregulation of periodontal ligament cell phenotype and functions by transforming growth factor-beta1.Semantic proximity Read ↗

Bone morphogenetic proteins: Signaling periodontal bone regeneration and repairSemantic proximity Read ↗

Periodontitis promotes the proliferation and suppresses the differentiation potential of human periodontal ligament stem cellsSemantic proximity Read ↗

Regulation of Cell Proliferation, Apoptosis, and Carcinogenesis by ActivinSemantic proximity Read ↗

The profiling and analysis of gene expression in human periodontal ligament tissue and fibroblastsSemantic proximity Read ↗

Osteoblast-like properties of human periodontal ligament cells: an in vitro analysis.Semantic proximity Read ↗

Recombinant human bone morphogenetic protein-2 stimulates osteoblastic differentiation in cells isolated from human periodontal ligament.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.