Article
Autoregulation of periodontal ligament cell phenotype and functions by transforming growth factor-beta1.
Journal of dental research - 1 Oct 1998
Brady T A, Piesco N P, Buckley M J, Langkamp H H, Bowen L L, Agarwal S
Abstract excerpt
During orthodontic tooth movement, mechanical forces acting on periodontal ligament (PDL) cells induce the synthesis of mediators which alter the growth, differentiation, and secretory functions of cells of the PDL. Since the cells of the PDL represent a heterogeneous population, we examined mechanically stress-induced cytokine profiles in three separate clones of human osteoblast-like PDL cells. Of the four...
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