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Article

Golgi enlargement in Arf-depleted yeast cells is due to altered dynamics of cisternal maturation.

Journal of cell science - 1 Jan 2014

Bhave Madhura, Papanikou Effrosyni, Iyer Prasanna, Pandya Koushal, Jain Bhawik Kumar, Ganguly Abira, Sharma Chandrakala, Pawar Ketakee, Austin Jotham, Day Kasey J, Rossanese Olivia W, Glick Benjamin S, Bhattacharyya Dibyendu

Abstract excerpt

Regulation of the size and abundance of membrane compartments is a fundamental cellular activity. In Saccharomyces cerevisiae, disruption of the ADP-ribosylation factor 1 (ARF1) gene yields larger and fewer Golgi cisternae by partially depleting the Arf GTPase. We observed a similar phenotype with a thermosensitive mutation in Nmt1, which myristoylates and activates Arf. Therefore, partial depletion of Arf is a...

Topics

ADP-Ribosylation Factor 1
Biological Transport
Gene Expression Regulation, Fungal
Golgi Apparatus
Mutation
Myristic Acids
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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Identifiers

PMID: 24190882
DOI: 10.1242/jcs.140996
PMCID: PMC3874789

Genes

ARF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24190882-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Golgi enlargement in Arf-depleted yeast cells is due to altered dynamics of cisternal maturation.PMID 24190882Read ↗

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