Article
COPI is essential for Golgi cisternal maturation and dynamics.
Journal of cell science - 1 Sept 2016
Ishii Midori, Suda Yasuyuki, Kurokawa Kazuo, Nakano Akihiko
Abstract excerpt
Proteins synthesized in the endoplasmic reticulum (ER) are transported to the Golgi and then sorted to their destinations. For their passage through the Golgi, one widely accepted mechanism is cisternal maturation. Cisternal maturation is fulfilled by the retrograde transport of Golgi-resident proteins from later to earlier cisternae, and candidate carriers for this retrograde transport are coat protein complex I...
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